Friday, May 20, 2011

Halitosis and Bad Breath Symptoms

Halitosis and Bad Breath Symptoms
Other Names :Bad Breath, Breath odor, Mauvaise haleine (French), Mundgeruch (Deutsch), Slechte adem (Dutch), Mala respiraciĆ³n or Malo aliento (Spanish), Alito cattivo (Italiano) and more… Many names to one complicated situation, that has medical, dental and psychological aspects.

Definition:
Halitosis, or bad breath, is a term used to describe noticeably unpleasant odors exhaled in breathing—whether the smell is from an oral source due to bacteria or otherwise. Halitosis has a significant impact—personally and socially—on those who suffer from it or believe they do (halitophobia), and is estimated to be the third-most-frequent reason for seeking dental aid, following tooth decay and periodontal disease.

Decaying food remnants and bacteria are the primary causes for bad breath. Common symptoms visible in Halitosis patients are an off-white yellowish coating on your tongue, post-nasal dripping secondary to sinusitis, metallic or sour or bitter taste due to hormone level imbalance or chemotherapy, acute streptococcal tonsillitis coalesced with white patches, and a dry mouth known as Sjogren’s syndrome. No amount of dental flossing, brushing or mouth-washes are going to help in this socially unnerving syndrome.

Your mouth will emit foul odors to the extent that even your closest friend will be embarrassed to tell you so. Most bacterial matter in the mouth normally concentrates on the nether regions of the tongue. Bacteria that are anaerobic in nature are the main culprits that cause these obnoxious odors. These bacteria wholly encompass the insides of the mouth vis-a-vis saliva. Now, removing the off-white yellowish film coated on your tongue is not the solution nor will it work out in your favor.

A commonality among people suffering from ‘dry mouth’ foul breath is basically due to halitosis. Long standing Xerostomia or chronic dry mouth syndrome leads to some pathological changes in the mouth. Bacteria begin to concentrate on a high scale in the saliva, which inhibits evaporative symptoms instantaneously. Lack of saliva acts as a catalyst of foul odor emission and is at its most repulsive. Subsequently, acidosis takes place resulting in tooth decay due to demineralization. This disorder is acid-based homeostasis, which means an overload of acid in the mouth and normally defined by the pH value falling well below 7.35. Such an atmosphere strongly generates oral bacteria. This syndrome is diagnosed by the patient having a metallic, sour or bitter taste in the mouth.

Acute streptococcal tonsillitis that have, over a period of time, accumulated ensconcing white patches are another cause of bad breath. These white patches are in the form of nodules and emit smelly odors from the mouth.

Continuous drug use, dependency on insulin, post-nasal drainage secondary to acute sinusitis, improperly done dental transplants, oral bacteria and gradual reduction of saliva in the mouth are major causes for bad breath and dental diseases.

Halitosis should be nipped in the bud. If ignored, you will be susceptible to a host of oral and dental illnesses. No, medicines or drugs will not cure it. Research its underlying causes, study the situation thoroughly well, and come to a conclusion as to what exactly is causing this unwanted foul smell emanating from your mouth. Act now, and take care that you do not lose your self-confidence, social connectivity, friends and self esteem in the process. The adage goes that: ‘An Apple a Day Keeps the Doctor Away’. This doggone adage goes” “Bad Breath Keeps Your Partner Away”. Permanently remove this enemy number one totally from your life and be respected in society.

There are ,however, three serious illnesses which can all give specific mouth odours:
* Liver failure causes a fishy odour (fetor hepaticus)
* Kidney failure an ammonia odour, and
* Diabetic coma (ketoacidosis) a fruity odour.

Finally, many healthy individuals have persistent bad breath through poor digestion. (There is no research suggesting a connection with hormonal cycles although it is well known that menopausal symptoms can affect digestion and the functioning of the body organs mentioned above.)

Examination of the mouth will yield the diagnosis when dental infection is responsible. A history of cough, fever and weight loss may suggest bronchiectasis or lung abscess. Diabetic ketoacidosis, liver disease and kidney failure each have a characteristic constellation of symptoms and physical and laboratory abnormalities. It is for these reasons that a full consultation and diagnosis be sought to identify the cause of the problem.

Tongue
The most common location for mouth-related halitosis is the tongue. Tongue bacteria produce malodorous compounds and fatty acids, and account for 80 to 90 percent of all cases of mouth-related bad breath.[6] Large quantities of naturally-occurring bacteria are often found on the posterior dorsum of the tongue, where they are relatively undisturbed by normal activity. This part of the tongue is relatively dry and poorly cleansed, and bacterial populations can thrive on remnants of food deposits, dead epithelial cells, and postnasal drip. The convoluted microbial structure of the tongue dorsum provides an ideal habitat for anaerobic bacteria, which flourish under a continually-forming tongue coating of food debris, dead cells, postnasal drip and overlying bacteria, living and dead. When left on the tongue, the anaerobic respiration of such bacteria can yield either the putrescent smell of indole, skatole, polyamines, or the “rotten egg” smell of volatile sulfur compounds (VSCs) such as hydrogen sulfide, methyl mercaptan, Allyl methyl sulfide, and dimethyl sulfide.

Cleaning the tongue
The most widely-known reason to clean the tongue is for the control of bad breath. Methods used against bad breath, such as mints, mouth sprays, mouthwash or gum, may only temporarily mask the odors created by the bacteria on the tongue, but cannot cure bad breath because they do not remove the source of the bad breath. In order to prevent the production of the sulfur-containing compounds mentioned above, the bacteria on the tongue must be removed, as must the decaying food debris present on the rear areas of the tongue. Most people who clean their tongue use a tongue cleaner (tongue scraper), or a toothbrush. Specially designed tongue cleaners are a lot more effective (collecting and removing the bacterial coating) than toothbrushes (which merely spread the bacterial accumulations on the tongue and in the mouth).

Mouth
There are over 600 types of bacteria found in the average mouth. Several dozen of these can produce high levels of foul odors when incubated in the laboratory. The odors are produced mainly due to the breakdown of proteins into individual amino acids, followed by the further breakdown of certain amino acids to produce detectable foul gases. For example, the breakdown of cysteine and methionine produce hydrogen sulfide and methyl mercaptan, respectively. Volatile sulfur compounds have been shown to be statistically associated with oral malodor levels, and usually decrease following successful treatment.

Other parts of the mouth may also contribute to the overall odor, but are not as common as the back of the tongue. These locations are, in order of descending prevalence: inter-dental and sub-gingival niches, faulty dental work, food-impaction areas in-between the teeth, abscesses, and unclean dentures. Oral based lesions caused by viral infections like Herpes Simplex and HPV may also contribute to bad breath.

Gum disease
There is some controversy over the role of periodontal diseases in causing bad breath. Whereas bacteria growing below the gumline (subgingival dental plaque) have a foul smell upon removal, several studies reported no statistical correlation between malodor and periodontal parameters.

Nose
The second major source of bad breath is the nose. In this occurrence, the air exiting the nostrils has a pungent odor that differs from the oral odor. Nasal odor may be due to sinus infections or foreign bodies.

Tonsils
In general, putrefaction from the tonsils is considered a minor cause of bad breath, contributing to some 3–5% of cases. Approximately 7% of the population suffer from small bits of calcified matter in tonsillar crypts called tonsilloliths that smell extremely foul when released and can cause bad breath.

Esophagus
Part 6 shown in the diagram is the Cardia.
The Cardia, which is the valve between the stomach and the esophagus, may not close properly due to a Hiatal Hernia or GERD, allowing acid to enter the esophagus and gases escape to the mouth. A Zenker’s diverticulum may also result in halitosis due to aging food retained in the esophagus.

Stomach
The stomach is considered by most researchers as a very uncommon source of bad breath (except in belching). The esophagus is a closed and collapsed tube, and continuous flow (as opposed to a simple burp) of gas or putrid substances from the stomach indicates a health problem—such as reflux serious enough to be bringing up stomach contents or a fistula between the stomach and the esophagus—which will demonstrate more serious manifestations than just foul odor.

In the case of allyl methyl sulfide (the byproduct of garlic’s digestion), odor does not come from the stomach, since it does not get metabolized there.

Systemic diseases
There are a few systemic (non-oral) medical conditions that may cause foul breath odor, but these are extremely infrequent in the general population. Such conditions are:

1.Fetor hepaticus: an example of a rare type of bad breath caused by chronic liver failure.
2.Lower respiratory tract infections (bronchial and lung infections).
3.Renal infections and renal failure.
4.Carcinoma.
5.Trimethylaminuria (“fish odor syndrome”).
6.Diabetes mellitus.
7.Metabolic dysfunction.
Individuals afflicted by the above conditions often show additional, more diagnostically conclusive symptoms than bad breath. People troubled by bad breath should not conclude that they suffer from these conditions or disease.

Diagnosis
Self diagnosis

Scientists have long thought that smelling one’s own breath odor is often difficult due to acclimatization, although many people with bad breath are able to detect it in others. Research has suggested that self-evaluation of halitosis is not easy because of preconceived notions of how bad we think it should be. Some people assume that they have bad breath because of bad taste (metallic, sour, fecal, etc.), however bad taste is considered a poor indicator.

For these reasons, the simplest and most effective way to know whether one has bad breath is to ask a trusted adult family member or very close friend (“confidant”). If the confidant confirms that there is a breath problem, he or she can help determine whether it is coming from the mouth or the nose, and whether a particular treatment is effective or not.

One popular home method to determine the presence of bad breath is to lick the back of the wrist, let the saliva dry for a minute or two, and smell the result. This test results in overestimation, as concluded from research, and should be avoided. A better way would be to lightly scrape the posterior back of the tongue with a plastic disposable spoon and to smell the drying residue. Home tests that use a chemical reaction to test for the presence of polyamines and sulfur compounds on tongue swabs are now available, but there are few studies showing how well they actually detect the odor. Furthermore, since breath odor changes in intensity throughout the day depending on many factors, multiple testing sessions may be necessary.

Professional diagnosis:
If bad breath is persistent, and all other medical and dental factors have been ruled out, specialized testing and treatment is required. Hundreds of dental offices and commercial breath clinics now claim to diagnose and treat bad breath. They often use some of several laboratory methods for diagnosis of bad breath:

1.Halimeter: a portable sulfide monitor used to test for levels of sulfur emissions (to be specific, hydrogen sulfide) in the mouth air. When used properly, this device can be very effective at determining levels of certain VSC-producing bacteria. However, it has drawbacks in clinical applications. For example, other common sulfides (such as mercaptan) are not recorded as easily and can be misrepresented in test results. Certain foods such as garlic and onions produce sulfur in the breath for as long as 48 hours and can result in false readings. The Halimeter is also very sensitive to alcohol, so one should avoid drinking alcohol or using alcohol-containing mouthwashes for at least 12 hours prior to being tested. This analog machine loses sensitivity over time and requires periodic recalibration to remain accurate.

2.Gas chromatography: portable machines, such as the OralChroma, are currently being introduced. This technology is specifically designed to digitally measure molecular levels of the three major VSCs in a sample of mouth air (hydrogen sulfide, methyl mercaptan, and dimethyl sulfide). It is accurate in measuring the sulfur components of the breath and produces visual results in graph form via computer interface.
3.BANA test: this test is directed to find the salivary levels of an enzyme indicating the presence of certain halitosis-related bacteria.
4.?-galactosidase test: salivary levels of this enzyme were found to be correlated with oral malodor.
Although such instrumentation and examinations are widely used in breath clinics, the most important measurement of bad breath (the gold standard) is the actual sniffing and scoring of the level and type of the odor carried out by trained experts (“organoleptic measurements”). The level of odor is usually assessed on a six-point intensity scale

Treatment:
Teeth brushing, flossing, mouthwashes and breath mints are effective in many instances, but these yield only temporary, symptomatic relief. Although bad breath is a common complaint, identifying the cause and developing an appropriate treatment plan can be difficult. The underlying cause must be identified before the appropriate therapy/remedy can be chosen. In all cases, the first thing to do is to consult your dentist to check that the cause does not lie in the mouth.

Mouthwashes: – Remember, mouthwashes are only applicable when the source of the problem lies with bacteria in the mouth. Remember also that a mouthwash is symptomatic treatment and does not treat the underlying cause (eg. bacterial growth in a cavity).

A two-phase (ie. oil-water) mouthwash has recently been developed because many oral microorganisms possess hydrophobic outer surfaces and may therefore arequireoil/water base to remove such oral microorganisms.

In one study (1) olive oil and other essential oils was mixed with an aqueous phase including cetylpyridinium chloride, which is a disinfectant that promotes the adhesion of microorganisms to oil droplets. This study found that whereas a reduction of only 30% of sulfide was observed when a commercial mouthwash was used, this two-phase mouthwash led to approximately 80% reduction of sulfide. Furthermore, volatile sulfide and 2-ketobutyrate in saliva putrefaction system were completely inhibited by the two-phase mouthwash. It concluded that the two-phase mouthwash strongly inhibits the production of volatile sulfide and is therefore a valuable help in eliminating bad breath.

The mouthwash, Listerine, is a solution for washing the oral cavity consisting of essential oils (thymol, methanol, eukalyptol) and methyl salicylate. One study (2) found that Listerine inhibited the growth of microorganisms over a very broad range. The bactericidal action of Listerine against from bacteria isolated from saliva and dental plaque from 5 healthy normal subjects was tested. Listerine exhibited a potent bactericidal effect on bacteria in saliva and dental plaque. Most of the bacteria died after a 30 second exposure to Listerine. According to the results, Listerine therefore does appear to be effective as a solution used for cleansing the oral cavity and dentures.


At the current time, chronic halitosis is not very well understood by most physicians and dentists, so effective treatment is not always easy to find. Six strategies may be suggested:

1.Gently cleaning the tongue surface twice daily is the most effective way to keep bad breath in control; that can be achieved using a tongue cleaner or tongue brush/scraper to wipe off the bacterial biofilm, debris, and mucus. An inverted teaspoon may also do the job; a toothbrush should be avoided, as the bristles only spread the bacteria in the mouth, and grip the tongue, causing a gagging reflex. Scraping or otherwise damaging the tongue should be avoided, and scraping of the V-shaped row of taste buds found at the extreme back of the tongue should also be avoided. Brushing a small amount of antibacterial mouth rinse or tongue gel onto the tongue surface will further inhibit bacterial action.

2.Eating a healthy breakfast with rough foods helps clean the very back of the tongue.

3.Chewing gum: Since dry-mouth can increase bacterial buildup and cause or worsen bad breath, chewing sugarless gum can help with the production of saliva, and thereby help to reduce bad breath. Chewing may help particularly when the mouth is dry, or when one cannot perform oral hygiene procedures after meals (especially those meals rich in protein). This aids in provision of saliva, which washes away oral bacteria, has antibacterial properties and promotes mechanical activity which helps cleanse the mouth. Some chewing gums contain special anti-odor ingredients. Chewing on fennel seeds, cinnamon sticks, mastic gum, or fresh parsley are common folk remedies.

4.Gargling right before bedtime with an effective mouthwash (see below). Several types of commercial mouthwashes have been shown to reduce malodor for hours in peer-reviewed scientific studies. Mouthwashes may contain active ingredients that are inactivated by the soap present in most toothpastes. Thus it is recommended to refrain from using mouthwash directly after toothbrushing with paste (also see mouthwashes, below).

5.Maintaining proper oral hygiene, including daily tongue cleaning, brushing, flossing, and periodic visits to dentists and hygienists. Flossing is particularly important in removing rotting food debris and bacterial plaque from between the teeth, especially at the gumline. Dentures should be properly cleaned and soaked overnight in antibacterial solution (unless otherwise advised by your dentist).

Mouthwashes
Before discussing them, it is important to note that there has not been a single documented medical case of successfully cured chronic halitosis using any of the currently available mouthwashes. Mouthwashes often contain antibacterial agents including cetylpyridinium chloride, chlorhexidine, zinc gluconate, essential oils, and chlorine dioxide. Zinc and chlorhexidine provide strong synergistic effect. They may also contain alcohol, which is a drying agent. Rinses in this category include Scope and Listerine.

Other solutions rely on odor eliminators like oxidizers to eliminate existing bad breath on a short-term basis.

A relatively new approach for home-care of bad breath is by oil-containing mouthwashes. The use of essential oils has been studied, was found effective and is being used in several commercial mouthwashes, as well as the use of two-phase (oil:water) mouthwashes, which have been found to be effective in reducing oral malodor. also advances in oral science has made advice websites available world wide.

Traditional remedies
According to traditional Ayurvedic medicine, chewing areca nut and betel leaf is an excellent remedy against bad breath. In South Asia, it was a custom to chew areca or betel nut and betel leaf among lovers because of the breath-freshening and stimulant drug properties of the mixture. Both the nut and the leaf are mild stimulants and can be addictive with repeated use. The betel nut will also cause tooth decay and dye one’s teeth bright red when chewed.[34]

Society and culture
Bad breath often evokes a reaction characteristic of disgust among those who interact with bad breath sufferers. This is a natural defensive reaction designed to protect the body from potential sources of disease: The major chemical compounds of bad breath are the same as those emitted by rotting food (Putrescine), feces (Skatole), and even dead bodies (Cadaverine), all potential sources of disease and infection.

When the brain detects these compounds, it protects the body by forcing physical recoil (which moves the body away), scrunching up the nose (which constricts the nasal passages, and prevents further intake of noxious odors), and by causing gagging (which stops anything being swallowed). It may also produce nausea and vomiting, which ejects anything that has already been swallowed. Although these reactions are involuntary, they are often misinterpreted as a personal judgement on the sufferer, and can severely damage personal relationships.

Research
In 1996, the International Society for Breath Odor Research (ISBOR) was formed to promote multidisciplinary research on all aspects of breath odors. The eighth international conference on breath odor took place in 2009 in Dortmund, Germany.

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